Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 9/20 | 0.42 |
| ▸ | LMNA | P02545 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29956884 | 0.88 | SMN1; SMN2 (0.47) | SMN1; SMN2MAPTLMNAALDH1A1NPSR1 | |
| SCHEMBL15331536 | 0.88 | PTGS2 (0.40) | SMN1; SMN2MAPTLMNARAB9AMAPK1 | |
| SCHEMBL2571901 | 0.87 | KMT2A (0.42) | SMN1; SMN2MAPTLMNAALDH1A1NPSR1 | |
| SCHEMBL2559349 | 0.87 | MAPT (0.40) | SMN1; SMN2MAPTLMNAALDH1A1NPSR1 | |
| SCHEMBL15330926 | 0.87 | SMN1; SMN2 (0.31) | SMN1; SMN2MAPTLMNAALDH1A1NPSR1 | |
| SCHEMBL2558267 | 0.85 | MAPT (0.41) | SMN1; SMN2MAPTLMNAALDH1A1NPSR1 | |
| SCHEMBL2559442 | 0.85 | MAPT (0.37) | SMN1; SMN2MAPTLMNAALDH1A1NPSR1 | |
| SCHEMBL2557372 | 0.85 | IDO1 (0.37) | MAPTLMNATP53MEN1KMT2A | |
| SCHEMBL29923212 | 0.85 | IDO1 (0.37) | MAPTLMNATP53MEN1KMT2A | |
| SCHEMBL15332195 | 0.84 | NPBWR1 (0.34) | SMN1; SMN2MAPTLMNAALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |