Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | ATR | Q13535 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1006953 | 1.00 | NLRP3 (0.43) | NLRP3SYKATRLCKALDH1A1 | |
| SCHEMBL1610508 | 0.88 | NLRP3 (0.53) | NLRP3SYKATRLCKALDH1A1 | |
| SCHEMBL3780741 | 0.84 | RXFP1 (0.43) | ATRLCKRXFP1LMNAPOLB | |
| SCHEMBL5349934 | 0.82 | LCK (0.51) | NLRP3SYKATRLCK | |
| SCHEMBL31167626 | 0.82 | LCK (0.51) | NLRP3SYKATRLCK | |
| SCHEMBL29954566 | 0.81 | ERN1 (0.42) | NLRP3SYKATRLCKALDH1A1 | |
| SCHEMBL2968874 | 0.81 | ERN1 (0.42) | NLRP3SYKATRLCKALDH1A1 | |
| SCHEMBL1677060 | 0.81 | ENPP2 (0.45) | ATRLCKALDH1A1GAA | |
| SCHEMBL23054108 | 0.81 | HTT (0.45) | NLRP3SYKATRLCKALDH1A1 | |
| SCHEMBL29741502 | 0.81 | HDAC1 (0.51) | NLRP3SYKATRLCKALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |