Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 2/20 | 0.41 |
| ▸ | CES1 | P23141 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | IKBKB | O14920 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | BRAF | P15056 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL909599 | 0.79 | CES2 (0.61) | GAACES2CES1NPC1RAB9A | |
| SCHEMBL9938748 | 0.79 | KEAP1 (0.50) | GAACES2CES1HPGDKDM4E | |
| SCHEMBL1743546 | 0.79 | SLC6A4 (0.46) | GAACES2CES1NPC1RAB9A | |
| SCHEMBL7980249 | 0.78 | GAA (0.48) | GAACES2CES1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL29775858 | 0.78 | CES2 (0.59) | GAACES2CES1NPC1RAB9A | |
| SCHEMBL1774955 | 0.78 | GAA (0.48) | GAACES2CES1NPC1RAB9A | |
| SCHEMBL7981585 | 0.76 | F2R (0.51) | GAACES2CES1NPC1RAB9A | |
| SCHEMBL705662 | 0.76 | HDAC1 (0.48) | GAACES2CES1HPGDKDM4E | |
| SCHEMBL883798 | 0.76 | HPGD (0.61) | GAANPC1RAB9AHPGD | |
| SCHEMBL30786133 | 0.76 | GAA (0.47) | GAACES2CES1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |