Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.39 |
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | TACR2 | P21452 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MGMT | P16455 | 1/20 | 0.36 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15330861 | 0.86 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2RAB9ANPC1MAPT | |
| SCHEMBL2559291 | 0.85 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2RAB9ANPC1MAPT | |
| SCHEMBL2557419 | 0.85 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2RAB9ANPC1MAPT | |
| SCHEMBL2560367 | 0.84 | TACR2 (0.56) | ALDH1A1SMN1; SMN2RAB9ANPC1MAPT | |
| SCHEMBL2556416 | 0.82 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2MAPTHTTALDH1A3 | |
| SCHEMBL29958389 | 0.81 | RAB9A (0.47) | ALDH1A1SMN1; SMN2RAB9AMAPTMAOA | |
| SCHEMBL2558592 | 0.79 | MAPT (0.45) | ALDH1A1SMN1; SMN2RAB9ANPC1MAPT | |
| SCHEMBL15332130 | 0.78 | PTGDR2 (0.55) | ALDH1A1RAB9ANPC1MAPTPTPN1 | |
| SCHEMBL29951459 | 0.77 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2RAB9ANPC1MAPT | |
| SCHEMBL29956332 | 0.77 | MAOB (0.63) | ALDH1A1SMN1; SMN2RAB9ANPC1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |