Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | CHUK | O15111 | 1/20 | 0.43 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | PRKCG | P05129 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955403 | 1.00 | S1PR3 (0.44) | S1PR3MEN1NR1I2LMNACHRM2 | |
| SCHEMBL29953363 | 1.00 | S1PR3 (0.44) | S1PR3MEN1NR1I2LMNACHRM2 | |
| SCHEMBL29952280 | 0.98 | S1PR3 (0.42) | S1PR3MEN1NR1I2LMNACHRM2 | |
| SCHEMBL3316395 | 0.94 | FAAH (0.43) | MEN1LMNAHTR2BKMT2AESR1 | |
| SCHEMBL263259 | 0.89 | HTR2C (0.46) | MEN1MAPTHTR2BKMT2AALDH1A1 | |
| SCHEMBL9945990 | 0.84 | FAAH (0.41) | MEN1LMNAHTR2BKMT2AESR1 | |
| SCHEMBL29957474 | 0.83 | GAA (0.49) | S1PR3MEN1MAPTKMT2ATHRA | |
| SCHEMBL29955818 | 0.83 | GAA (0.49) | S1PR3MEN1MAPTKMT2ATHRA | |
| SCHEMBL29957059 | 0.83 | GAA (0.49) | S1PR3MEN1MAPTKMT2ATHRA | |
| SCHEMBL29952296 | 0.82 | L3MBTL1 (0.42) | MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |