SCHEMBL29956380

SCHEMBL29956380

C[Si](C)(C)CCOCn1cnc(B(O)O)c1

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.33
NPC1 O15118 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2822834 0.79 DGAT1 (0.38) DGAT1
SCHEMBL5764924 0.78 KDM4E (0.35) DGAT1NPC1
SCHEMBL31091884 0.78 DGAT1 (0.37) DGAT1
SCHEMBL1396117 0.78 DGAT1 (0.37) DGAT1NPC1
SCHEMBL19924651 0.78 DGAT1 (0.34) DGAT1
SCHEMBL111672 0.78 DGAT1 (0.34) DGAT1
SCHEMBL2147273 0.78 DGAT1 (0.42) DGAT1
SCHEMBL22093251 0.76 DGAT1 (0.34) DGAT1
SCHEMBL2473549 0.76 DGAT1 (0.34) DGAT1
SCHEMBL5092069 0.76 PLA2G4A (0.38) DGAT1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed