Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 2/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SLC13A5 | Q86YT5 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16225784 | 1.00 | HPGD (0.43) | HPGDSMN1; SMN2LRRK2GRM5NPC1 | |
| SCHEMBL29951146 | 0.81 | CCR1 (0.33) | NOS2NOS3ALDH1A1MAPT | |
| SCHEMBL16225239 | 0.81 | CCR1 (0.33) | NOS2NOS3ALDH1A1MAPT | |
| SCHEMBL22121997 | 0.75 | KDM4E (0.37) | HPGDSMN1; SMN2ALDH1A1MAPK1RAB9A | |
| SCHEMBL16231386 | 0.75 | HPGD (0.50) | HPGDSMN1; SMN2LRRK2GRM5NPC1 | |
| SCHEMBL17473788 | 0.74 | L3MBTL1 (0.46) | HPGDSMN1; SMN2TSHRALDH1A1L3MBTL1 | |
| SCHEMBL16110848 | 0.72 | CCR1 (0.38) | NOS2NOS3 | |
| SCHEMBL29954504 | 0.72 | CCR1 (0.38) | NOS2NOS3 | |
| SCHEMBL12903576 | 0.72 | HPGD (0.47) | HPGDSMN1; SMN2LRRK2GRM5NPC1 | |
| SCHEMBL5942693 | 0.72 | HPGD (0.47) | HPGDSMN1; SMN2LRRK2GRM5NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |