Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.62 |
| ▸ | NQO2 | P16083 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.51 |
| ▸ | HPGD | P15428 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15330099 | 0.80 | ALDH1A1 (0.54) | ALDH1A1NQO2KDM4EHPGDMEN1 | |
| SCHEMBL15331314 | 0.80 | ALDH1A1 (0.54) | ALDH1A1NQO2KDM4EHPGDMEN1 | |
| SCHEMBL29954088 | 0.80 | AHR (0.58) | ALDH1A1KDM4EMEN1KMT2AGAA | |
| SCHEMBL29955208 | 0.78 | ALDH1A1 (0.56) | ALDH1A1NQO2KDM4EHPGDMEN1 | |
| SCHEMBL15332265 | 0.78 | ALDH1A1 (0.52) | ALDH1A1NQO2KDM4EHPGDMEN1 | |
| SCHEMBL9452783 | 0.78 | KDM4E (0.63) | ALDH1A1NQO2KDM4EHPGDMEN1 | |
| SCHEMBL15332034 | 0.77 | ALDH1A1 (0.54) | ALDH1A1NQO2KDM4EHPGDMEN1 | |
| SCHEMBL15331732 | 0.77 | ALDH1A1 (0.54) | ALDH1A1NQO2KDM4EHPGDMEN1 | |
| SCHEMBL6218141 | 0.77 | FEN1 (0.41) | ALDH1A1HPGDMEN1KMT2AMAPT | |
| SCHEMBL6218865 | 0.77 | ALDH1A1 (0.48) | ALDH1A1KDM4EHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |