Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.58 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.50 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KIF11 | P52732 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.43 |
| ▸ | RPA1 | P27694 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3242577 | 0.82 | PIM1 (0.48) | AHRTRIM24TRIM33MAPTKDM4E | |
| SCHEMBL6218865 | 0.82 | ALDH1A1 (0.48) | AHRMAPTKMT2AKDM4EMEN1 | |
| SCHEMBL6218141 | 0.82 | FEN1 (0.41) | AHRTRIM24TRIM33MAPTKMT2A | |
| SCHEMBL11850379 | 0.81 | PIM1 (0.51) | AHRTRIM24TRIM33MAPTKMT2A | |
| SCHEMBL29956415 | 0.80 | ALDH1A1 (0.62) | MAPTKMT2AGAAKDM4EMEN1 | |
| SCHEMBL15331976 | 0.80 | CCNB2 (0.47) | AHRTRIM24TRIM33MAPTKMT2A | |
| SCHEMBL29954233 | 0.80 | TRIM24 (0.45) | AHRTRIM24TRIM33MAPTKMT2A | |
| SCHEMBL29954778 | 0.78 | KDM4E (0.51) | AHRTRIM24TRIM33MAPTKMT2A | |
| SCHEMBL15330850 | 0.77 | TRIM24 (0.43) | AHRTRIM24TRIM33MAPTKMT2A | |
| SCHEMBL29952619 | 0.77 | TRIM24 (0.43) | AHRTRIM24TRIM33MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |