Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 11/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PIK3R1 | P27986 | 5/20 | 0.34 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL117586 | 1.00 | PIK3CA (0.38) | PIK3CAENPP2CA1CA2MAPT | |
| SCHEMBL20605929 | 0.87 | PIK3CA (0.37) | PIK3CAENPP2CA1CA2MAPT | |
| SCHEMBL14659133 | 0.82 | SYK (0.31) | — | |
| SCHEMBL3635036 | 0.79 | ENPP2 (0.36) | PIK3CAENPP2CA1CA2MAPT | |
| SCHEMBL29955940 | 0.79 | ENPP2 (0.36) | PIK3CAENPP2CA1CA2MAPT | |
| SCHEMBL24354976 | 0.79 | ENPP2 (0.36) | ENPP2CA1CA2MAPTKDR | |
| SCHEMBL22066589 | 0.79 | SYK (0.33) | — | |
| SCHEMBL1811195 | 0.78 | ENPP2 (0.40) | PIK3CAENPP2CA1CA2MAPT | |
| SCHEMBL29953456 | 0.78 | ENPP2 (0.40) | PIK3CAENPP2CA1CA2MAPT | |
| SCHEMBL30788168 | 0.78 | MAPT (0.49) | PIK3CAENPP2CA1CA2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |