Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 2/20 | 0.35 |
| ▸ | PTGES2 | Q9H7Z7 | 3/20 | 0.33 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.32 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1811195 | 1.00 | ENPP2 (0.40) | ENPP2LMNACYP2C9TSHRAPEX1 | |
| SCHEMBL14120573 | 0.82 | RORC (0.39) | ENPP2LMNACYP2C9TSHRAPEX1 | |
| SCHEMBL16734291 | 0.81 | RORC (0.37) | ENPP2LMNACYP2C9TSHRAPEX1 | |
| SCHEMBL29955039 | 0.80 | ENPP2 (0.34) | ENPP2LMNACYP2C9TSHRAPEX1 | |
| SCHEMBL24354976 | 0.79 | ENPP2 (0.36) | ENPP2CA1CA2CYP3A4MAPT | |
| SCHEMBL3635036 | 0.79 | ENPP2 (0.36) | ENPP2CA1CA2PIK3CAMAPT | |
| SCHEMBL20605929 | 0.79 | PIK3CA (0.37) | ENPP2CA1CA2PIK3CAMAPT | |
| SCHEMBL29955940 | 0.79 | ENPP2 (0.36) | ENPP2CA1CA2PIK3CAMAPT | |
| SCHEMBL366465 | 0.78 | SCN9A (0.44) | CYP2C9CYP3A4 | |
| SCHEMBL29956760 | 0.78 | BCHE (0.38) | ENPP2LMNACYP2C9TSHRAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |