Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.67 |
| ▸ | LIPE | Q05469 | 1/20 | 0.66 |
| ▸ | PTGER1 | P34995 | 7/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1333263 | 1.00 | ENPP2 (0.67) | ENPP2LIPEPTGER1HTR2CHTR2B | |
| SCHEMBL5110136 | 0.88 | ENPP2 (0.67) | ENPP2LIPEPTGER1HTR2CHTR2B | |
| SCHEMBL4720905 | 0.85 | ENPP2 (0.56) | ENPP2LIPEPTGER1SLC6A4MRGPRX4 | |
| SCHEMBL5103313 | 0.84 | PTGER1 (0.63) | ENPP2LIPEPTGER1CYP2C9 | |
| SCHEMBL28606699 | 0.83 | LIPE (0.68) | ENPP2LIPE | |
| SCHEMBL1753346 | 0.83 | LIPE (0.68) | ENPP2LIPEPTGER1MRGPRX4CYP2C9 | |
| SCHEMBL5109980 | 0.81 | LIPE (0.66) | ENPP2LIPEPTGER1SLC6A4 | |
| SCHEMBL1956146 | 0.81 | LIPE (0.71) | ENPP2LIPEPTGER1MRGPRX4 | |
| SCHEMBL29825616 | 0.81 | LIPE (0.71) | ENPP2LIPEPTGER1MRGPRX4 | |
| SCHEMBL2557075 | 0.81 | LIPE (0.75) | ENPP2LIPECYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4562000-A1 | AMINOHETEROARYL KINASE INHIBITORS | Allorion Therapeutics Inc (US) | 2025-06-04 | — | — | EP | disclosed |
| CN-119630652-A | Amino heteroaryl kinase inhibitors | 安锐生物医药公司 | 2025-03-14 | — | — | CN | disclosed |
| WO-2024022487-A1 | AMINOHETEROARYL KINASE INHIBITORS | Allorion Therapeutics Inc (US) | 2024-02-01 | — | — | WO | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |