Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | VNN1 | O95497 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.33 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.33 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30753556 | 0.79 | HCAR3 (0.48) | KDM4EALDH1A1L3MBTL1KCNJ1CYP2A6 | |
| SCHEMBL2766191 | 0.79 | HCAR3 (0.48) | KDM4EALDH1A1L3MBTL1KCNJ1CYP2A6 | |
| SCHEMBL3922829 | 0.76 | KDR (0.45) | KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL19630947 | 0.76 | HCAR3 (0.54) | KDM4EALDH1A1L3MBTL1KCNJ1CYP2A6 | |
| SCHEMBL4099418 | 0.75 | KDM4E (0.44) | KDM4EALDH1A1L3MBTL1POLBKCNJ1 | |
| SCHEMBL29958408 | 0.74 | HCAR3 (0.53) | KDM4EALDH1A1L3MBTL1KCNJ1CYP2A6 | |
| SCHEMBL28420434 | 0.73 | KDM4E (0.40) | KDM4EALDH1A1L3MBTL1POLBKCNJ1 | |
| SCHEMBL29883804 | 0.73 | KDM4E (0.40) | KDM4EALDH1A1L3MBTL1POLBKCNJ1 | |
| SCHEMBL29955270 | 0.73 | HCAR3 (0.57) | KDM4EALDH1A1L3MBTL1KCNJ1ALDH3A1 | |
| SCHEMBL3301252 | 0.73 | PTK2 (0.59) | KDM4EALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |