Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 1/20 | 0.48 |
| ▸ | NNMT | P40261 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.38 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.36 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.36 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2766191 | 1.00 | HCAR3 (0.48) | HCAR3NNMTKCNH2KDM4EALDH1A1 | |
| SCHEMBL19630947 | 0.80 | HCAR3 (0.54) | HCAR3KDM4EALDH1A1L3MBTL1KCNJ1 | |
| SCHEMBL3664466 | 0.79 | KCNH2 (0.45) | HCAR3NNMTKCNH2ALDH1A1CPB2 | |
| SCHEMBL4099418 | 0.79 | KDM4E (0.44) | KDM4EALDH1A1L3MBTL1KCNJ1CYP2A6 | |
| SCHEMBL29958408 | 0.79 | HCAR3 (0.53) | HCAR3KDM4EALDH1A1L3MBTL1KCNJ1 | |
| SCHEMBL29956458 | 0.79 | KDM4E (0.39) | KDM4EALDH1A1L3MBTL1KCNJ1CYP2A6 | |
| SCHEMBL28420434 | 0.77 | KDM4E (0.40) | KDM4EALDH1A1L3MBTL1KCNJ1SMN1; SMN2 | |
| SCHEMBL29955270 | 0.77 | HCAR3 (0.57) | HCAR3KDM4EALDH1A1L3MBTL1KCNJ1 | |
| SCHEMBL29882896 | 0.77 | PTK2 (0.59) | KDM4EALDH1A1L3MBTL1MAPT | |
| SCHEMBL3301252 | 0.77 | PTK2 (0.59) | KDM4EALDH1A1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117098764-A | Tetrahydrothienopyridine derivatives as DDR inhibitors | 奇斯药制品公司 | 2023-11-21 | — | — | CN | disclosed |