Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 8/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | G6PD | P11413 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | KDM4B | O94953 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3404328 | 0.79 | ALDH1A1 (0.46) | ADORA2ALMNAHTTADORA3ADORA2B | |
| SCHEMBL9520789 | 0.75 | KDM4E (0.50) | ADORA2ALMNAHTTADORA3ADORA2B | |
| SCHEMBL21352421 | 0.74 | ADORA2A (0.44) | ADORA2ALMNAHTTADORA3ADORA2B | |
| SCHEMBL8363953 | 0.74 | ADORA2A (0.44) | ADORA2ALMNAHTTADORA3ADORA2B | |
| SCHEMBL27904488 | 0.74 | ADORA2A (0.47) | ADORA2ALMNAHTTADORA3ADORA2B | |
| SCHEMBL16815526 | 0.73 | LMNA (0.41) | ADORA2ALMNAHTTADORA3ADORA2B | |
| Hydrochloric Acid SCHEMBL28376383 | 0.72 | ADORA2A (0.46) | ADORA2ALMNAHTTADORA3ADORA2B | |
| SCHEMBL32810 | 0.71 | KDM4E (0.46) | ADORA2ALMNAHTTADORA3ADORA2B | |
| Hydrochloric Acid SCHEMBL28375706 | 0.71 | ADORA2A (0.45) | ADORA2ALMNAHTTADORA3ADORA2B | |
| Hydrochloric Acid SCHEMBL28374859 | 0.71 | ADORA2A (0.45) | ADORA2ALMNAHTTADORA3ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |