Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.42 |
| ▸ | TUBB | P07437 | 1/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.42 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.42 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.42 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.42 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.42 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.42 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.42 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2561474 | 0.88 | ALDH1A1 (0.45) | ALDH1A1MAPK1POLBSMN1; SMN2MAPT | |
| SCHEMBL2558197 | 0.87 | ALDH1A1 (0.71) | ALDH1A1MAPK1POLBSMN1; SMN2MAPT | |
| SCHEMBL532027 | 0.86 | ALDH1A1 (0.49) | ALDH1A1MAPK1POLBSMN1; SMN2MAPT | |
| SCHEMBL5340763 | 0.84 | ALDH1A1 (0.56) | ALDH1A1MAPK1SMN1; SMN2MAPTHPGD | |
| SCHEMBL14835718 | 0.81 | ALDH1A1 (0.50) | ALDH1A1MAPK1POLBSMN1; SMN2MAPT | |
| SCHEMBL2559587 | 0.81 | ALDH1A1 (0.64) | ALDH1A1MAPK1POLBSMN1; SMN2MAPT | |
| SCHEMBL29087050 | 0.80 | ALDH1A1 (0.49) | ALDH1A1MAPK1POLBSMN1; SMN2MAPT | |
| SCHEMBL29954001 | 0.80 | ALDH1A1 (0.66) | ALDH1A1POLBSMN1; SMN2MAPTHPGD | |
| SCHEMBL29957232 | 0.80 | ALDH1A1 (0.66) | ALDH1A1POLBSMN1; SMN2MAPTHPGD | |
| SCHEMBL7821448 | 0.79 | ALDH1A1 (0.51) | ALDH1A1POLBSMN1; SMN2MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |