Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.66 |
| ▸ | MAPT | P10636 | 9/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15331542 | 0.91 | KMT2A (0.58) | ALDH1A1MAPTSMN1; SMN2POLBCTDSP1 | |
| SCHEMBL29954001 | 0.90 | ALDH1A1 (0.66) | ALDH1A1MAPTSMN1; SMN2POLBKMT2A | |
| SCHEMBL29954289 | 0.88 | ALDH1A1 (0.51) | ALDH1A1MAPTSMN1; SMN2POLBCTDSP1 | |
| SCHEMBL2561787 | 0.88 | ALDH1A1 (0.64) | ALDH1A1MAPTSMN1; SMN2POLBCTDSP1 | |
| SCHEMBL15330685 | 0.87 | MAPT (0.51) | ALDH1A1MAPTSMN1; SMN2POLBCTDSP1 | |
| SCHEMBL29955385 | 0.87 | MAPT (0.51) | ALDH1A1MAPTSMN1; SMN2POLBCTDSP1 | |
| SCHEMBL2559178 | 0.86 | SMN1; SMN2 (0.50) | ALDH1A1MAPTSMN1; SMN2POLBCTDSP1 | |
| SCHEMBL15330441 | 0.84 | MAPT (0.53) | ALDH1A1MAPTSMN1; SMN2POLBCTDSP1 | |
| SCHEMBL2557303 | 0.84 | MAPT (0.52) | ALDH1A1MAPTSMN1; SMN2POLBCTDSP1 | |
| SCHEMBL531660 | 0.84 | ALDH1A1 (0.54) | ALDH1A1MAPTSMN1; SMN2POLBCTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |