Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 2/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TERT | O14746 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13724354 | 0.78 | GRM4 (0.53) | GRM4SMN1; SMN2POLB | |
| SCHEMBL27261834 | 0.78 | CCR1 (0.37) | ERN1CCR1HTTLMNATERT | |
| SCHEMBL29952455 | 0.77 | ALDH1A1 (0.36) | GRM4CCR1LMNAALDH1A1KDM4E | |
| SCHEMBL3089372 | 0.77 | ALDH1A1 (0.36) | GRM4CCR1LMNAALDH1A1KDM4E | |
| SCHEMBL7472288 | 0.77 | HTR2B (0.35) | CCR1HTR2B | |
| SCHEMBL13926087 | 0.77 | NOS2 (0.46) | GRM4LMNA | |
| SCHEMBL891790 | 0.75 | — | — | |
| SCHEMBL11026593 | 0.75 | GAA (0.42) | GRM4HTTMAPK1SMN1; SMN2KDM4E | |
| SCHEMBL11026594 | 0.75 | GAA (0.42) | GRM4HTTMAPK1SMN1; SMN2KDM4E | |
| SCHEMBL21338123 | 0.74 | CCR1 (0.32) | GRM4CCR1LMNAPOLBAPOBEC3G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |