Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR17 | Q13304 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.53 |
| ▸ | GAA | P10253 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.49 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.49 |
| ▸ | GSK3A | P49840 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.48 |
| ▸ | TUBB | P07437 | 1/20 | 0.48 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1429238 | 0.89 | KDM4E (0.59) | KDM4EGAAALDH1A1HSD17B10HPGD | |
| SCHEMBL29956404 | 0.89 | KDM4E (0.59) | KDM4EGAAALDH1A1HSD17B10HPGD | |
| SCHEMBL4877545 | 0.87 | KDM4E (0.67) | GPR17KDM4EGAAALDH1A1HSD17B10 | |
| SCHEMBL9253578 | 0.83 | ALOX15 (0.72) | KDM4EGAAALDH1A1HSD17B10HPGD | |
| SCHEMBL1144751 | 0.82 | GPR17 (0.64) | GPR17KDM4EGAAALDH1A1HSD17B10 | |
| SCHEMBL30779683 | 0.81 | GPR17 (0.63) | GPR17KDM4EGAAALDH1A1HSD17B10 | |
| SCHEMBL14154118 | 0.80 | KDM4E (0.57) | KDM4EGAAALDH1A1HSD17B10HPGD | |
| SCHEMBL29954171 | 0.79 | MEN1 (0.50) | GPR17KDM4EGAAALDH1A1HSD17B10 | |
| SCHEMBL28873648 | 0.79 | KDM4E (0.59) | KDM4EALDH1A1HSD17B10HPGDMAPT | |
| SCHEMBL4877546 | 0.78 | GPR17 (0.60) | GPR17KDM4EGAAALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |