Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 6/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.62 |
| ▸ | HPGD | P15428 | 6/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 4/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.51 |
| ▸ | TUBB | P07437 | 4/20 | 0.51 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.51 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.51 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7250379 | 0.90 | ALDH1A1 (0.73) | ALOX15ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL37221912 | 0.90 | ALDH1A1 (0.73) | ALOX15ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL4877545 | 0.87 | KDM4E (0.67) | ALOX15ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL9260498 | 0.86 | ALOX15 (0.77) | ALOX15ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL1120783 | 0.84 | ALDH1A1 (0.80) | ALOX15ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL29955347 | 0.84 | ALOX15 (0.73) | ALOX15ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL28640836 | 0.84 | ALOX15 (0.73) | ALOX15ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL29954264 | 0.84 | ALOX15 (0.73) | ALOX15ALDH1A1KDM4EHPGDMAPT | |
| SCHEMBL469602 | 0.84 | ALOX15 (1.00) | ALOX15 | |
| SCHEMBL8794611 | 0.83 | ALDH1A1 (0.66) | ALOX15ALDH1A1KDM4EHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-5428043-A | Tricyclic-cyclic amines as novel cholinesterase inhibitors | PFIZER INC. (US) | 1995-06-27 | — | — | US | disclosed |
| EP-0441517-A2 | Tricyclic amines as novel cholinesterase inhibitors | PFIZER INC. (US) | 1991-08-14 | — | — | EP | disclosed |