SCHEMBL2995654

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12091792	0.86	PLA2G10 (0.57)	PLA2G10FOLH1KDM4EKDM4AKDM4C
	SCHEMBL2985652	0.85	KDM4E (0.54)	PLA2G10FOLH1KDM4ETSHRKMT2A
	SCHEMBL2993846	0.84	KDM4E (0.46)	PLA2G10FOLH1KDM4ETSHRKMT2A
	SCHEMBL2981842	0.83	TSHR (0.42)	PLA2G10FOLH1KDM4ETSHRKMT2A
	SCHEMBL2987944	0.82	KDM4E (0.45)	PLA2G10FOLH1KDM4ETSHRKMT2A
	SCHEMBL2997360	0.82	KDM4E (0.46)	PLA2G10FOLH1KDM4EKDM4AKDM4C
	SCHEMBL2997006	0.82	KMO (0.49)	PLA2G10FOLH1KDM4ETSHRKMT2A
	SCHEMBL2999469	0.81	MDM2 (0.46)	PLA2G10FOLH1KDM4ETSHRKMT2A
	SCHEMBL12092457	0.81	KDM4E (0.51)	PLA2G10FOLH1KDM4EKDM4CTSHR
	SCHEMBL2996320	0.81	KDM4E (0.47)	PLA2G10FOLH1KDM4ETSHRKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.