Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | PRKDC | P78527 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19172679 | 0.84 | SMN1; SMN2 (0.50) | SMN1; SMN2TSHRCYP3A4GPR35KDM4E | |
| SCHEMBL13341541 | 0.83 | SMN1; SMN2 (0.49) | SMN1; SMN2TSHRCYP3A4GPR35KDM4E | |
| SCHEMBL16302853 | 0.79 | SMN1; SMN2 (0.46) | SMN1; SMN2TSHRCYP3A4GPR35KDM4E | |
| SCHEMBL203719 | 0.79 | ERN1 (0.47) | SMN1; SMN2CYP3A4KDM4EMAPTALDH1A1 | |
| SCHEMBL1991890 | 0.79 | TDP1 (0.39) | CYP3A4KDM4EMAPTLMNAALDH1A1 | |
| SCHEMBL203806 | 0.79 | VCAM1 (0.42) | TSHRGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL761929 | 0.77 | SMN1; SMN2 (0.57) | SMN1; SMN2TSHRCYP3A4GPR35KDM4E | |
| SCHEMBL12161594 | 0.76 | SMN1; SMN2 (0.56) | SMN1; SMN2TSHRCYP3A4GPR35KDM4E | |
| SCHEMBL16302885 | 0.75 | SMN1; SMN2 (0.48) | SMN1; SMN2TSHRCYP3A4GPR35KDM4E | |
| SCHEMBL19712001 | 0.75 | ALDH1A1 (0.49) | SMN1; SMN2TSHRCYP3A4KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |