Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.50 |
| ▸ | LIPE | Q05469 | 1/20 | 0.48 |
| ▸ | BCL2 | P10415 | 1/20 | 0.48 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.48 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16225686 | 1.00 | LIPG (0.50) | LIPGLIPEBCL2BCL2L1CALM1 | |
| SCHEMBL25625118 | 0.88 | CA1 (0.45) | LIPGLIPEBCL2BCL2L1KEAP1 | |
| SCHEMBL29116248 | 0.86 | LIPG (0.46) | LIPGLIPEKEAP1LMNAMEN1 | |
| SCHEMBL19616322 | 0.84 | BCL2 (0.47) | LIPEBCL2BCL2L1ALOX5 | |
| SCHEMBL29940325 | 0.83 | LIPE (0.42) | LIPGLIPEBCL2BCL2L1CALM1 | |
| SCHEMBL28796057 | 0.83 | LIPE (0.42) | LIPGLIPEBCL2BCL2L1CALM1 | |
| SCHEMBL5987891 | 0.81 | LIPG (0.48) | LIPGLMNAHPGDKMT2A | |
| SCHEMBL29014484 | 0.81 | LIPG (0.58) | LIPGLIPEHTTKMT2A | |
| SCHEMBL12989233 | 0.80 | FOLH1 (0.50) | KMT2AHIF1A | |
| SCHEMBL31051099 | 0.77 | BCL2 (0.44) | LIPEBCL2BCL2L1CALM1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |