Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2554036 | 0.85 | SIGMAR1 (0.38) | SIGMAR1KDM4EALDH1A1ATMMEN1 | |
| SCHEMBL29952380 | 0.82 | KDM4E (0.35) | SIGMAR1KDM4ELMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL15330120 | 0.82 | SIGMAR1 (0.38) | SIGMAR1KDM4EALDH1A1KDM1AATM | |
| SCHEMBL2553398 | 0.81 | SIGMAR1 (0.40) | SIGMAR1KDM4EALDH1A1SMN1; SMN2ATM | |
| SCHEMBL29957327 | 0.79 | SIGMAR1 (0.42) | SIGMAR1KDM4EALDH1A1SMN1; SMN2ATM | |
| SCHEMBL29955335 | 0.79 | KDM4E (0.51) | SIGMAR1KDM4ELMNAALDH1A1KDM1A | |
| SCHEMBL2558352 | 0.78 | SIGMAR1 (0.41) | SIGMAR1KDM4EALDH1A1SMN1; SMN2ATM | |
| SCHEMBL2554344 | 0.78 | SIGMAR1 (0.35) | SIGMAR1KDM4ELMNAALDH1A1KDM1A | |
| SCHEMBL29955444 | 0.77 | KDM4E (0.59) | SIGMAR1KDM4ELMNAALDH1A1ATM | |
| SCHEMBL2561392 | 0.77 | SIGMAR1 (0.46) | SIGMAR1KDM4ELMNAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |