Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.30 |
| ▸ | PEPD | P12955 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2555485 | 0.87 | POLB (0.37) | KDM4ESIGMAR1ALDH1A1HSD11B1 | |
| SCHEMBL15330412 | 0.84 | KDM4E (0.37) | KDM4ESIGMAR1ALDH1A1ATMHSD11B1 | |
| SCHEMBL2562021 | 0.84 | KDM4E (0.37) | KDM4ESIGMAR1ALDH1A1ATMHSD11B1 | |
| SCHEMBL29956562 | 0.82 | SIGMAR1 (0.38) | KDM4ESIGMAR1LMNAALDH1A1ATM | |
| SCHEMBL29956109 | 0.82 | KDM4E (0.50) | KDM4ESIGMAR1ALDH1A1HSD11B1 | |
| SCHEMBL29957083 | 0.81 | KDM4E (0.56) | KDM4ESIGMAR1LMNAALDH1A1ATM | |
| SCHEMBL2559874 | 0.81 | KDM4E (0.35) | KDM4ESIGMAR1ALDH1A1ATMHSD11B1 | |
| SCHEMBL29957401 | 0.81 | ALDH1A1 (0.38) | KDM4ESIGMAR1LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL15332186 | 0.80 | SIGMAR1 (0.37) | KDM4ESIGMAR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL2559097 | 0.78 | KDM4E (0.36) | KDM4ESIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |