Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | SRC | P12931 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.45 |
| ▸ | TLR2 | O60603 | 1/20 | 0.44 |
| ▸ | ERN1 | O75460 | 1/20 | 0.44 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.44 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2559159 | 0.90 | GAA (0.41) | RAB9ANPC1ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL2554537 | 0.87 | NPC1 (0.52) | RAB9ANPC1SRCALDH1A1NFE2L2 | |
| SCHEMBL29952197 | 0.87 | ALDH1A1 (0.56) | RAB9ANPC1SRCALDH1A1NFE2L2 | |
| SCHEMBL29954807 | 0.84 | ALDH1A1 (0.57) | RAB9ANPC1SRCALDH1A1TSHR | |
| SCHEMBL2559195 | 0.84 | NPC1 (0.49) | RAB9ANPC1SRCALDH1A1NFE2L2 | |
| SCHEMBL29951179 | 0.82 | MAPT (0.49) | RAB9ANPC1SRCALDH1A1L3MBTL1 | |
| SCHEMBL2558191 | 0.82 | NPC1 (0.54) | RAB9ANPC1SRCALDH1A1NFE2L2 | |
| SCHEMBL20150688 | 0.81 | NPC1 (0.51) | RAB9ANPC1SRCALDH1A1NFE2L2 | |
| SCHEMBL637742 | 0.81 | NPC1 (0.61) | RAB9ANPC1SRCALDH1A1NFE2L2 | |
| SCHEMBL2557845 | 0.79 | GAA (0.42) | RAB9ANPC1SRCALDH1A1TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |