Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | RAD52 | P43351 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955221 | 0.87 | PTGDR2 (0.62) | ALDH1A1SMN1; SMN2HPGDHTTPTGDR2 | |
| SCHEMBL15331738 | 0.85 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2HPGDHTTPTGDR2 | |
| SCHEMBL2559159 | 0.84 | GAA (0.41) | ALDH1A1SMN1; SMN2HPGDHTTPTGDR2 | |
| SCHEMBL29956589 | 0.84 | RAB9A (0.50) | ALDH1A1SMN1; SMN2HPGDTSHRNPC1 | |
| SCHEMBL29955065 | 0.81 | ALDH1A1 (0.52) | ALDH1A1HPGDTSHRRAB9A | |
| SCHEMBL2560058 | 0.81 | SMN1; SMN2 (0.56) | ALDH1A1SMN1; SMN2HPGDHTTPTGDR2 | |
| SCHEMBL15331648 | 0.81 | TSHR (0.64) | ALDH1A1SMN1; SMN2HPGDTSHRMEN1 | |
| SCHEMBL11783241 | 0.80 | ALDH1A1 (0.62) | ALDH1A1SMN1; SMN2HPGDHTTPTGDR2 | |
| SCHEMBL29955345 | 0.80 | KDM4E (0.60) | ALDH1A1SMN1; SMN2HPGDTSHRRAB9A | |
| SCHEMBL15332303 | 0.80 | HPGD (0.50) | ALDH1A1HPGDTSHRNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |