Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ERN1 | O75460 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.41 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953474 | 0.89 | ALDH1A1 (0.53) | RAB9ACYP2D6MAPK1MAPTKDM4E | |
| SCHEMBL2559153 | 0.88 | CYP2D6 (0.47) | RAB9ACYP2D6MAPK1MAPTERN1 | |
| SCHEMBL2557533 | 0.81 | ERN1 (0.50) | RAB9ACYP2D6MAPK1MAPTERN1 | |
| SCHEMBL215546 | 0.81 | CYP19A1 (0.54) | RAB9ACYP2D6MAPK1MAPTERN1 | |
| SCHEMBL15331648 | 0.80 | TSHR (0.64) | MAPK1MAPTKDM4EHPGDTSHR | |
| SCHEMBL15331888 | 0.80 | KMT2A (0.49) | RAB9ACYP2D6MAPK1MAPTKDM4E | |
| SCHEMBL29954289 | 0.80 | ALDH1A1 (0.51) | CYP2D6MAPTKDM4EHTTHPGD | |
| SCHEMBL28825735 | 0.79 | MAPT (0.55) | RAB9ACYP2D6MAPK1MAPTERN1 | |
| SCHEMBL31327257 | 0.79 | MAPT (0.55) | RAB9ACYP2D6MAPK1MAPTERN1 | |
| SCHEMBL4998777 | 0.79 | MAPT (0.56) | RAB9ACYP2D6MAPK1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |