Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ERN1 | O75460 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15331888 | 0.91 | KMT2A (0.49) | ALDH1A1MAPTLMNASMN1; SMN2KDM4E | |
| SCHEMBL29956643 | 0.89 | RAB9A (0.46) | ALDH1A1MAPTLMNASMN1; SMN2KDM4E | |
| SCHEMBL2561464 | 0.88 | ALDH1A1 (0.51) | ALDH1A1MAPTLMNASMN1; SMN2KDM4E | |
| SCHEMBL29956598 | 0.87 | MAPT (0.46) | ALDH1A1MAPTLMNASMN1; SMN2KDM4E | |
| SCHEMBL2556198 | 0.87 | ALDH1A1 (0.46) | ALDH1A1MAPTLMNASMN1; SMN2KDM4E | |
| SCHEMBL2556381 | 0.86 | SMN1; SMN2 (0.50) | ALDH1A1MAPTLMNASMN1; SMN2KDM4E | |
| SCHEMBL2563279 | 0.84 | SMN1; SMN2 (0.58) | ALDH1A1MAPTLMNASMN1; SMN2KDM4E | |
| SCHEMBL7359228 | 0.84 | RAB9A (0.44) | ALDH1A1MAPTLMNASMN1; SMN2RAB9A | |
| SCHEMBL3997757 | 0.84 | ALDH1A1 (0.60) | ALDH1A1MAPTLMNASMN1; SMN2KDM4E | |
| SCHEMBL2552640 | 0.83 | MAPT (0.48) | ALDH1A1MAPTLMNASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |