Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 8/20 | 0.45 |
| ▸ | CDK8 | P49336 | 1/20 | 0.45 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | CLK2 | P49760 | 5/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 5/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 4/20 | 0.43 |
| ▸ | FLT4 | P35916 | 4/20 | 0.43 |
| ▸ | KDR | P35968 | 4/20 | 0.43 |
| ▸ | FLT3 | P36888 | 4/20 | 0.43 |
| ▸ | FRK | P42685 | 4/20 | 0.43 |
| ▸ | CAMK2B | Q13554 | 4/20 | 0.43 |
| ▸ | CAMK2G | Q13555 | 4/20 | 0.43 |
| ▸ | CAMK2D | Q13557 | 4/20 | 0.43 |
| ▸ | NTRK3 | Q16288 | 4/20 | 0.43 |
| ▸ | PKN2 | Q16513 | 4/20 | 0.43 |
| ▸ | PRKD2 | Q9BZL6 | 4/20 | 0.43 |
| ▸ | SLK | Q9H2G2 | 4/20 | 0.43 |
| ▸ | SGK2 | Q9HBY8 | 4/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953681 | 0.77 | CDK8 (0.50) | AXLCDK8CLK2CLK4PRKD3 | |
| SCHEMBL24323860 | 0.77 | CCR1 (0.39) | PIM1MAPK1HASPIN | |
| SCHEMBL29600275 | 0.77 | CCR1 (0.39) | PIM1MAPK1HASPIN | |
| SCHEMBL24324039 | 0.73 | CCR1 (0.39) | ITKMAPK1BTK | |
| SCHEMBL771611 | 0.72 | CAMKK2 (0.55) | AXLCDK8TNIKPARP1CLK2 | |
| SCHEMBL13045978 | 0.72 | DYRK1A (0.76) | AXLCDK8TNIKCLK2CLK4 | |
| SCHEMBL13834371 | 0.70 | LRRK2 (0.49) | DYRK1AROCK2IMPDH2ROCK1CDC42BPA | |
| SCHEMBL11467387 | 0.70 | CSNK2A2 (0.48) | CSNK2A1 | |
| SCHEMBL29952518 | 0.70 | AXL (0.70) | AXLCDK8TNIKCLK2CLK4 | |
| SCHEMBL2830315 | 0.69 | CCR1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |