Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.46 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.46 |
| ▸ | NOS2 | P35228 | 6/20 | 0.46 |
| ▸ | NOS3 | P29474 | 5/20 | 0.46 |
| ▸ | NOS1 | P29475 | 5/20 | 0.46 |
| ▸ | LSS | P48449 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | LPL | P06858 | 1/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31082165 | 0.88 | HRH3 (0.54) | LTA4HHRH3HRH4LPLLIPG | |
| SCHEMBL29951372 | 0.83 | SIGMAR1 (0.50) | KDM4EALDH1A1LTA4HHRH3HRH4 | |
| SCHEMBL3979242 | 0.83 | HRH3 (0.68) | KDM4EALDH1A1LTA4HHRH3HRH4 | |
| SCHEMBL29952597 | 0.83 | HRH3 (0.68) | KDM4EALDH1A1LTA4HHRH3HRH4 | |
| SCHEMBL24495214 | 0.82 | HRH3 (0.49) | KDM4EALDH1A1LTA4HHRH3HRH4 | |
| SCHEMBL29953942 | 0.82 | HRH3 (0.49) | LTA4HHRH3HRH4LPLLIPG | |
| SCHEMBL8251941 | 0.81 | HTR2A (0.58) | KDM4EALDH1A1LTA4HHRH3HRH4 | |
| SCHEMBL13887902 | 0.81 | KDM4E (0.58) | KDM4EALDH1A1LTA4HHRH3HRH4 | |
| SCHEMBL18412166 | 0.80 | KDM4E (0.57) | KDM4EALDH1A1LTA4HHRH3HRH4 | |
| SCHEMBL17286021 | 0.80 | NOS2 (0.59) | KDM4EALDH1A1LTA4HHRH3HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |