Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1156315 | 0.85 | ALDH1A1 (0.54) | ENPP2ALDH1A1GAALMNATP53 | |
| SCHEMBL2854999 | 0.81 | ENPP2 (0.46) | ENPP2TSHRALDH1A1GAATTR | |
| SCHEMBL29956646 | 0.81 | ENPP2 (0.46) | ENPP2TSHRALDH1A1GAATTR | |
| SCHEMBL29952606 | 0.81 | ALDH1A1 (0.46) | ENPP2TDP1ALDH1A1GAALMNA | |
| SCHEMBL2558072 | 0.79 | ALDH1A1 (0.44) | ENPP2ALDH1A1GAAKDM1AMAPT | |
| SCHEMBL29953019 | 0.79 | CSNK2A1 (0.44) | ENPP2L3MBTL1ALDH1A1GAATTR | |
| SCHEMBL4881084 | 0.79 | CSNK2A1 (0.44) | ENPP2L3MBTL1ALDH1A1GAATTR | |
| SCHEMBL29954995 | 0.78 | TTR (0.42) | ENPP2GAATTRLMNAMEN1 | |
| SCHEMBL23363515 | 0.77 | ENPP2 (0.43) | ENPP2L3MBTL1ALDH1A1TTRLMNA | |
| SCHEMBL29899161 | 0.77 | ENPP2 (0.43) | ENPP2L3MBTL1ALDH1A1TTRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |