Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | BRD2 | P25440 | 1/20 | 0.30 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.30 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955220 | 1.00 | ADAMTS5 (0.40) | ADAMTS5NR3C1BRD4BRD2BRD3 | |
| SCHEMBL29953135 | 0.98 | ADAMTS5 (0.38) | ADAMTS5BRD4BRD2BRD3CREBBP | |
| SCHEMBL29956772 | 0.85 | MAPK13 (0.32) | ADAMTS5 | |
| SCHEMBL29955455 | 0.85 | MAPK13 (0.32) | ADAMTS5 | |
| SCHEMBL29957598 | 0.84 | MAPK13 (0.30) | — | |
| SCHEMBL853448 | 0.77 | ALDH1A1 (0.39) | NR3C1BRD4BRD2BRD3CREBBP | |
| SCHEMBL853226 | 0.77 | ALDH1A1 (0.39) | NR3C1BRD4BRD2BRD3CREBBP | |
| SCHEMBL29954547 | 0.77 | — | — | |
| SCHEMBL29953694 | 0.77 | — | — | |
| SCHEMBL854856 | 0.75 | ALDH1A1 (0.37) | NR3C1BRD4BRD2BRD3CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |