Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 12/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15329728 | 0.84 | HSD11B1 (0.39) | HSD11B1 | |
| SCHEMBL29952445 | 0.84 | HSD11B1 (0.44) | HSD11B1TRPA1 | |
| SCHEMBL15330833 | 0.82 | MAPT (0.38) | HSD11B1CYP1A2CYP2D6CYP2C19KDM4E | |
| SCHEMBL15331588 | 0.81 | MAPT (0.43) | HSD11B1CYP1A2CYP2C19ALDH1A1TDP1 | |
| SCHEMBL15329967 | 0.80 | CYP1A2 (0.39) | HSD11B1CYP1A2CYP2C19KDM4EALDH1A1 | |
| SCHEMBL15332541 | 0.79 | HSD11B1 (0.40) | HSD11B1CYP1A2CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL28709406 | 0.77 | HSD11B1 (0.43) | HSD11B1CYP1A2CYP2D6CYP2C19CYP3A4 | |
| SCHEMBL2555076 | 0.77 | CYP1A2 (0.37) | HSD11B1CYP1A2CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL29952633 | 0.77 | CYP1A2 (0.37) | HSD11B1CYP1A2CYP2D6CYP2C19ALDH1A1 | |
| SCHEMBL15332242 | 0.77 | BRD4 (0.45) | CYP1A2CYP2C19CYP3A4KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |