Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 14/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15331593 | 0.84 | HSD11B1 (0.39) | HSD11B1TRPA1PIK3R1PIK3CASLC22A12 | |
| SCHEMBL29956816 | 0.84 | HSD11B1 (0.44) | HSD11B1TRPA1 | |
| SCHEMBL15332547 | 0.82 | MAPT (0.36) | — | |
| SCHEMBL29952755 | 0.82 | LMNA (0.38) | HSD11B1 | |
| SCHEMBL15331461 | 0.81 | HSD11B1 (0.36) | HSD11B1 | |
| SCHEMBL15330112 | 0.80 | TDP2 (0.38) | — | |
| SCHEMBL15330084 | 0.79 | HSD11B1 (0.40) | HSD11B1 | |
| SCHEMBL15330811 | 0.77 | HSD11B1 (0.35) | HSD11B1PIK3R1PIK3CA | |
| SCHEMBL15331147 | 0.77 | BRD4 (0.48) | — | |
| SCHEMBL29954023 | 0.75 | CSF1R (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |