Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | LDHA | P00338 | 1/20 | 0.38 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26091851 | 0.87 | SMN1; SMN2 (0.68) | SMN1; SMN2TSHRMAPTFAAHKMT2A | |
| SCHEMBL3459599 | 0.81 | SMN1; SMN2 (0.68) | SMN1; SMN2TSHRMAPTFAAHKMT2A | |
| SCHEMBL9047027 | 0.79 | SMN1; SMN2 (0.54) | SMN1; SMN2TSHRMAPTFAAHKMT2A | |
| SCHEMBL1958588 | 0.79 | SMN1; SMN2 (0.81) | SMN1; SMN2TSHRMAPTFAAHKMT2A | |
| SCHEMBL1417131 | 0.78 | SMN1; SMN2 (0.58) | SMN1; SMN2TSHRMAPTFAAHKMT2A | |
| SCHEMBL4068835 | 0.78 | SMN1; SMN2 (0.58) | SMN1; SMN2TSHRMAPTFAAHKMT2A | |
| SCHEMBL6881087 | 0.78 | TSHR (0.83) | SMN1; SMN2TSHRMAPTFAAHHTT | |
| SCHEMBL3594562 | 0.78 | MAPT (0.83) | SMN1; SMN2TSHRMAPTFAAHHTT | |
| SCHEMBL5494155 | 0.77 | — | — | |
| SCHEMBL206601 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |