SCHEMBL4068835

SCHEMBL4068835

C=CCNC(=O)CC(N)=O

nearest known ligand 0.58

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.58
TSHR P16473 2/20 0.58
MAPT P10636 2/20 0.58
ALDH1A1 P00352 3/20 0.50
FAAH O00519 1/20 0.47
KMT2A Q03164 3/20 0.43
MEN1 O00255 2/20 0.41
KDM4E B2RXH2 1/20 0.40
GAA P10253 2/20 0.39
RAB9A P51151 3/20 0.38
HTT P42858 2/20 0.38
GLA P06280 1/20 0.38
HPGD P15428 2/20 0.37
HSD17B10 Q99714 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26091851 0.85 SMN1; SMN2 (0.68) SMN1; SMN2TSHRMAPTALDH1A1FAAH
SCHEMBL7375016 0.82 SMN1; SMN2 (0.65) SMN1; SMN2TSHRMAPTALDH1A1FAAH
SCHEMBL10898374 0.80 TSHR (0.83) SMN1; SMN2TSHRMAPTALDH1A1FAAH
SCHEMBL8003437 0.80 SMN1; SMN2 (0.52) SMN1; SMN2TSHRMAPTALDH1A1FAAH
SCHEMBL1264763 0.78
SCHEMBL29956817 0.78 SMN1; SMN2 (0.60) SMN1; SMN2TSHRMAPTALDH1A1FAAH
SCHEMBL9242577 0.77 ALDH1A1 (0.38) SMN1; SMN2TSHRMAPTALDH1A1
SCHEMBL1958588 0.77 SMN1; SMN2 (0.81) SMN1; SMN2TSHRMAPTALDH1A1FAAH
SCHEMBL29510 0.77
SCHEMBL14780249 0.77 SMN1; SMN2 (0.48) SMN1; SMN2TSHRMAPTALDH1A1FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021099336-A1 METHOD FOR IMPROVING COEFFICIENT OF FRICTION IN CURED FLUORORUBBER PARTS SOLVAY SPECIALTY POLYMERS ITALY S.P.A. (IT) 2021-05-27 WO claimed
EP-1343837-A1 FLUOROELASTOMER FILMS PREPARED BY PEROXIDE CURING A WATER-BORNE FLUOROELASTOMER COATING Lauren International, Inc. (US) 2003-09-17 EP claimed
US-20020111417-A1 Fluoroelastomer films prepared by peroxide curing a water-borne fluoroelastomer coating LAUREN INTERNATIONAL, INC. 2002-08-15 US claimed
WO-2002048251-A1 FLUOROELASTOMER FILMS PREPARED BY PEROXIDE CURING A WATER-BORNE FLUOROELASTOMER COATING LAUREN INTERNATIONAL, INC. (US) 2002-06-20 WO claimed
EP-0010426-A1 Pharmaceutical composition containing 3,4-dihydro-3-oxo-2-quinoxalines, novel such quinoxalines and processes for the production thereof ELI LILLY AND COMPANY (US) 1980-04-30 EP claimed
WO-2009038006-A1 RANDOM COPOLYMER AND PRODUCTION PROCESS THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-03-26 WO disclosed
WO-2009038031-A1 BLOCK COPOLYMER AND PRODUCTION PROCESS THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-03-26 WO disclosed
EP-1343837-A1 FLUOROELASTOMER FILMS PREPARED BY PEROXIDE CURING A WATER-BORNE FLUOROELASTOMER COATING Lauren International, Inc. (US) 2003-09-17 EP disclosed
US-20020111417-A1 Fluoroelastomer films prepared by peroxide curing a water-borne fluoroelastomer coating LAUREN INTERNATIONAL, INC. 2002-08-15 US disclosed
WO-2002048251-A1 FLUOROELASTOMER FILMS PREPARED BY PEROXIDE CURING A WATER-BORNE FLUOROELASTOMER COATING LAUREN INTERNATIONAL, INC. (US) 2002-06-20 WO disclosed
EP-0654025-A4 METHOD OF PREPARING OPTICALLY PURE PRECURSORS OF PAROXETINE. SEPRACOR INC (US) 1995-10-11 EP disclosed
EP-0654025-A1 METHOD OF PREPARING OPTICALLY PURE PRECURSORS OF PAROXETINE SEPRACOR, INC. (US) 1995-05-24 EP disclosed
WO-1994003428-A1 METHOD OF PREPARING OPTICALLY PURE PRECURSORS OF PAROXETINE SEPRACOR, INC. (US) 1994-02-17 WO disclosed
US-5258517-A Method of preparing optically pure precursors of paroxetine SEPRACOR, INC. (US) 1993-11-02 US disclosed