Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
| ▸ | PTPRG | P23470 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | GRK6 | P43250 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PHGDH | O43175 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5632525 | 0.77 | CYP1A2 (0.46) | CYP1A2KMT2AFFAR1PTPRCALDH1A1 | |
| SCHEMBL266573 | 0.75 | KMT2A (0.47) | CYP1A2KMT2AFFAR1PTPRCALDH1A1 | |
| SCHEMBL10388521 | 0.74 | MAPT (0.42) | CYP1A2KMT2AALDH1A1KDM4EHPGD | |
| SCHEMBL9528983 | 0.72 | CYP1A2 (0.42) | CYP1A2KMT2AFFAR1ALDH1A1KDM4E | |
| SCHEMBL22832573 | 0.71 | CYP1A2 (0.41) | CYP1A2KMT2AFFAR1PTPRCALDH1A1 | |
| SCHEMBL5781162 | 0.70 | — | — | |
| SCHEMBL14560315 | 0.69 | AKR1B1 (0.44) | CYP1A2KMT2AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL7034585 | 0.68 | CYP1A2 (0.58) | CYP1A2KMT2AFFAR1ALDH1A1KDM4E | |
| SCHEMBL1465828 | 0.68 | SIRT1 (0.37) | KMT2APTPRCALDH1A1KDM4EHPGD | |
| SCHEMBL1158753 | 0.67 | KMT2A (0.43) | CYP1A2KMT2AFFAR1PTPRCALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |