Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.52 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CDC25B | P30305 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14273063 | 0.82 | CYP1A2 (0.73) | CYP1A2FFAR1KDM4EALDH1A1HPGD | |
| SCHEMBL9711982 | 0.79 | LMNA (0.48) | CYP1A2PTGDR2ALDH1A1HPGDMEN1 | |
| SCHEMBL14215044 | 0.76 | MCL1 (0.49) | CYP1A2KDM4EMEN1KMT2ABLM | |
| SCHEMBL3181540 | 0.76 | POLB (0.55) | CYP1A2ALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL979786 | 0.76 | MEN1 (0.44) | CYP1A2PTGDR2KDM4EALDH1A1HPGD | |
| SCHEMBL2801460 | 0.75 | LMNA (0.48) | CYP1A2PTGDR2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL6659512 | 0.75 | CYP1A2 (0.63) | CYP1A2FFAR1KDM4EALDH1A1HPGD | |
| SCHEMBL7402835 | 0.75 | CYP1A2 (0.63) | CYP1A2FFAR1KDM4EALDH1A1HPGD | |
| SCHEMBL28764582 | 0.74 | ALDH1A1 (0.46) | CYP1A2FFAR1PTGDR2ALDH1A1CDC25B | |
| SCHEMBL8676119 | 0.73 | CYP1A2 (0.61) | CYP1A2FFAR1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210230123-A1 | INHIBITORS OF ALPHA-AMINO-BETA-CARBOXYMUCONIC ACID SEMIALDEHYDE DECARBOXYLASE | TES PHARMA S.R.L. (IT) | 2021-07-29 | — | — | US | disclosed |
| US-20180134667-A1 | INHIBITORS OF ALPHA-AMINO-BETA-CARBOXYMUCONIC ACID SEMIALDEHYDE DECARBOXYLASE | TES PHARMA S.R.L. (IT) | 2018-05-17 | — | — | US | disclosed |
| WO-2018069532-A1 | INHIBITORS OF ALPHA-AMINO-BETA-CARBOXYMUCONIC ACID SEMIALDEHYDE DECARBOXYLASE | TES PHARMA S.R.L. (IT) | 2018-04-19 | — | — | WO | disclosed |
| WO-2007117180-A1 | AZAHETEROCYCLES, COMBINATORY LIBRARY, FOCUSED LIBRARY, PHARMACEUTICAL COMPOSITION AND METHODS FOR THE PRODUCTION THEREOF | 'CHEMICAL DIVERSITY RESEARCH INSTITUTE' LTD. (RU) | 2007-10-18 | — | — | WO | disclosed |
| EP-1064276-B1 | PROCESS FOR SYNTHESIZING SUBSTITUTED 2-BENZO b] THIOPHENE CARBOXYLIC ACIDS AND SALTS THEREOF | UNIROYAL CHEM CO INC (US) | 2003-02-26 | — | — | EP | disclosed |
| US-5965749-A | Process for synthesizing substituted 2-benzo [b]thiophenecarboxylic acids and salts thereof | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1999-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210230123-A1 | INHIBITORS OF ALPHA-AMINO-BETA-CARBOXYMUCONIC ACID SEMIALDEHYDE DECARBOXYLASE | ACMSD, GLS, ALDH7A1 | CYP1A2 1119/4885FFAR1 3480/4885PTGDR2 3221/4885 |
| US-20180134667-A1 | INHIBITORS OF ALPHA-AMINO-BETA-CARBOXYMUCONIC ACID SEMIALDEHYDE DECARBOXYLASE | ACMSD, GLS, ALDH7A1 | CYP1A2 1119/4885FFAR1 3480/4885PTGDR2 3221/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.