Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.43 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.42 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.42 |
| ▸ | CHUK | O15111 | 1/20 | 0.41 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | PRKCG | P05129 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29957474 | 0.98 | GAA (0.49) | MAPTALDH1A1GAATHRBNPSR1 | |
| SCHEMBL29957059 | 0.98 | GAA (0.49) | MAPTALDH1A1GAATHRBNPSR1 | |
| SCHEMBL29955818 | 0.98 | GAA (0.49) | MAPTALDH1A1GAATHRBNPSR1 | |
| SCHEMBL3318133 | 0.95 | KDM4E (0.45) | MAPTALDH1A1GAATHRBNPSR1 | |
| SCHEMBL3317396 | 0.90 | MAPT (0.48) | MAPTALDH1A1GAATHRBNPSR1 | |
| SCHEMBL9946008 | 0.85 | KDM4E (0.43) | MAPTALDH1A1GAATHRBNPSR1 | |
| SCHEMBL1490739 | 0.82 | MAPT (0.45) | MAPTALDH1A1GAANPSR1KDM4E | |
| SCHEMBL29956763 | 0.82 | MAPT (0.45) | MAPTALDH1A1GAANPSR1KDM4E | |
| SCHEMBL15331983 | 0.82 | L3MBTL1 (0.41) | MAPTALDH1A1NPSR1KDM4EMEN1 | |
| SCHEMBL29952280 | 0.82 | S1PR3 (0.42) | MAPTALDH1A1THRBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |