Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1490739 | 1.00 | MAPT (0.45) | MAPTL3MBTL1POLBRAB9AALDH1A1 | |
| SCHEMBL16687429 | 0.86 | MEN1 (0.38) | MAPTL3MBTL1POLBRAB9AALDH1A1 | |
| SCHEMBL3317396 | 0.85 | MAPT (0.48) | MAPTL3MBTL1POLBRAB9AALDH1A1 | |
| SCHEMBL2140990 | 0.85 | MAPT (0.45) | MAPTL3MBTL1POLBRAB9AALDH1A1 | |
| SCHEMBL15331983 | 0.84 | L3MBTL1 (0.41) | MAPTL3MBTL1POLBRAB9AALDH1A1 | |
| SCHEMBL3318133 | 0.84 | KDM4E (0.45) | MAPTL3MBTL1POLBRAB9AALDH1A1 | |
| SCHEMBL29956845 | 0.82 | MAPT (0.50) | MAPTL3MBTL1RAB9AALDH1A1ATM | |
| SCHEMBL2703903 | 0.81 | ACHE (0.39) | MAPTL3MBTL1POLBRAB9AALDH1A1 | |
| SCHEMBL29951021 | 0.81 | ACHE (0.39) | MAPTL3MBTL1POLBRAB9AALDH1A1 | |
| SCHEMBL29955818 | 0.81 | GAA (0.49) | MAPTL3MBTL1ALDH1A1HPGDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |