Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.47 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PIM3 | Q86V86 | 9/20 | 0.41 |
| ▸ | PIM1 | P11309 | 7/20 | 0.41 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.38 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.38 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | CCR8 | P51685 | 1/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23498199 | 0.81 | TDO2 (0.41) | ALDH1A1KDM4EMAPTKMT2A | |
| SCHEMBL29723651 | 0.81 | TDO2 (0.41) | ALDH1A1KDM4EMAPTKMT2A | |
| SCHEMBL29954589 | 0.79 | TRIM24 (0.56) | TRIM24TRIM33ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL29956271 | 0.77 | TRIM24 (0.49) | TRIM24TRIM33KMT2APIM3PIM1 | |
| SCHEMBL13909727 | 0.76 | PIM3 (0.48) | TRIM24TRIM33ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL29952712 | 0.76 | PIM3 (0.48) | TRIM24TRIM33ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL29954304 | 0.76 | TRIM24 (0.47) | TRIM24TRIM33ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL12693836 | 0.76 | KMT2A (0.47) | TRIM24TRIM33ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL29951661 | 0.76 | KMT2A (0.47) | TRIM24TRIM33ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL20673981 | 0.76 | PDPK1 (0.35) | ALDH1A1CYP1A2CYP2C19KDM4EPIM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |