Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 6/20 | 0.54 |
| ▸ | NPC1 | O15118 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | PPARA | Q07869 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ILK | Q13418 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CLK1 | P49759 | 1/20 | 0.43 |
| ▸ | CLK2 | P49760 | 1/20 | 0.43 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29951963 | 0.87 | CYP1A2 (0.59) | DYRK1ANPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL29955647 | 0.80 | PPARA (0.43) | DYRK1ANPC1RAB9ASMN1; SMN2PPARA | |
| SCHEMBL95067 | 0.80 | NPC1 (0.55) | DYRK1ANPC1RAB9ASMN1; SMN2PPARA | |
| SCHEMBL31276816 | 0.80 | NPC1 (0.55) | DYRK1ANPC1RAB9ASMN1; SMN2PPARA | |
| SCHEMBL11459521 | 0.78 | NPC1 (0.57) | DYRK1ANPC1RAB9ASMN1; SMN2PPARA | |
| SCHEMBL2400142 | 0.76 | NPC1 (0.55) | DYRK1ANPC1RAB9ASMN1; SMN2PPARA | |
| SCHEMBL29956381 | 0.76 | CA2 (0.54) | DYRK1ANPC1RAB9ASMN1; SMN2TP53 | |
| Perchlorate SCHEMBL11695399 | 0.75 | HSD17B10 (0.53) | DYRK1ANPC1RAB9ASMN1; SMN2PPARA | |
| SCHEMBL778048 | 0.75 | NPC1 (0.54) | DYRK1ANPC1RAB9ASMN1; SMN2PPARA | |
| SCHEMBL12318433 | 0.75 | NPC1 (0.54) | DYRK1ANPC1RAB9ASMN1; SMN2PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |