Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.42 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.37 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.37 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.37 |
| ▸ | LIPE | Q05469 | 1/20 | 0.36 |
| ▸ | KCNK3 | O14649 | 3/20 | 0.35 |
| ▸ | KCNK9 | Q9NPC2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29417492 | 0.82 | ENPP2 (0.57) | ENPP2ORAI1ORAI2ORAI3LIPE | |
| SCHEMBL264406 | 0.82 | ENPP2 (0.57) | ENPP2ORAI1ORAI2ORAI3LIPE | |
| SCHEMBL1044949 | 0.82 | ALDH1A1 (0.39) | KCNK3KCNK9ALDH1A1KDM4ELMNA | |
| SCHEMBL29951241 | 0.81 | ENPP2 (0.42) | ENPP2ORAI1ORAI2ORAI3LIPE | |
| SCHEMBL4877157 | 0.81 | ENPP2 (0.42) | ENPP2ORAI1ORAI2ORAI3LIPE | |
| SCHEMBL29957207 | 0.81 | ENPP2 (0.42) | ENPP2ORAI1ORAI2ORAI3LIPE | |
| SCHEMBL29955371 | 0.80 | ENPP2 (0.41) | ENPP2ORAI1ORAI2ORAI3LIPE | |
| SCHEMBL29953300 | 0.80 | ENPP2 (0.41) | ENPP2ORAI1ORAI2ORAI3LIPE | |
| SCHEMBL2446918 | 0.80 | ENPP2 (0.41) | ENPP2ORAI1ORAI2ORAI3LIPE | |
| SCHEMBL29955287 | 0.79 | ENPP2 (0.40) | ENPP2ORAI1ORAI2ORAI3LIPE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |