Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 4/20 | 0.33 |
| ▸ | AXL | P30530 | 2/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 3/20 | 0.32 |
| ▸ | TDO2 | P48775 | 1/20 | 0.32 |
| ▸ | CCR1 | P32246 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | CCR8 | P51685 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | METAP2 | P50579 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
| ▸ | RAF1 | P04049 | 1/20 | 0.30 |
| ▸ | BRAF | P15056 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30431003 | 0.82 | NOS1 (0.34) | NOS1AXLIDO1TDO2METAP2 | |
| SCHEMBL29575075 | 0.76 | NOS1 (0.55) | NOS1AXLIDO1LMNAMETAP2 | |
| SCHEMBL261171 | 0.76 | NOS1 (0.55) | NOS1AXLIDO1LMNAMETAP2 | |
| SCHEMBL27650245 | 0.74 | NOS1 (0.53) | NOS1AXLIDO1LMNAMETAP2 | |
| SCHEMBL23107877 | 0.72 | TDO2 (0.56) | NOS1AXLIDO1TDO2METAP2 | |
| SCHEMBL23107879 | 0.72 | IDO1 (0.54) | IDO1TDO2LMNAMETAP2RAF1 | |
| SCHEMBL1187899 | 0.71 | CYP2A6 (0.40) | CCNT1CDK9HASPIN | |
| Hydrogen Sulfide SCHEMBL27706806 | 0.69 | CYP2A6 (0.39) | CCNT1CDK9HASPIN | |
| SCHEMBL23092917 | 0.68 | TDO2 (0.43) | IDO1TDO2METAP2 | |
| SCHEMBL25111959 | 0.68 | NOS1 (0.55) | NOS1AXLIDO1TDO2METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |