Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 7/20 | 0.52 |
| ▸ | MAOB | P27338 | 7/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2557137 | 0.85 | GAA (0.57) | GAAALDH1A1SMN1; SMN2TSHRLMNA | |
| SCHEMBL19287101 | 0.84 | ALDH1A1 (0.62) | MAOAMAOBGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL2555866 | 0.76 | MAOA (0.55) | MAOAMAOBSMN1; SMN2KMT2ANPC1 | |
| SCHEMBL1633619 | 0.74 | MAOA (0.66) | MAOAMAOBNPC1RAB9ATDP1 | |
| SCHEMBL2557646 | 0.74 | PTGER4 (0.70) | MAOAMAOBALDH1A1POLBNPC1 | |
| SCHEMBL2559705 | 0.74 | NPC1 (0.62) | MAOAMAOBALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL30165933 | 0.73 | GAA (0.72) | GAAALDH1A1SMN1; SMN2TSHRLMNA | |
| SCHEMBL28588209 | 0.73 | GAA (0.72) | GAAALDH1A1SMN1; SMN2TSHRLMNA | |
| SCHEMBL2560564 | 0.71 | MAOA (0.52) | MAOAMAOBALDH1A1SMN1; SMN2POLB | |
| SCHEMBL31482043 | 0.70 | MAOA (0.73) | MAOAMAOBALDH1A1SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |