Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | CPA1 | P15085 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.37 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5126162 | 1.00 | SMN1; SMN2 (0.43) | SMN1; SMN2TSHRMEN1KMT2ALMNA | |
| SCHEMBL16556784 | 1.00 | SMN1; SMN2 (0.43) | SMN1; SMN2TSHRMEN1KMT2ALMNA | |
| SCHEMBL18180339 | 0.86 | SMN1; SMN2 (0.47) | SMN1; SMN2TSHRMEN1KMT2ALMNA | |
| SCHEMBL21202140 | 0.86 | SMN1; SMN2 (0.47) | SMN1; SMN2TSHRMEN1KMT2ALMNA | |
| SCHEMBL14365811 | 0.79 | SMN1; SMN2 (0.34) | SMN1; SMN2TSHRMEN1KMT2ALMNA | |
| SCHEMBL12304285 | 0.79 | ALDH1A1 (0.54) | SMN1; SMN2TSHRMEN1KMT2ALMNA | |
| SCHEMBL15154265 | 0.77 | MME (0.39) | SMN1; SMN2TSHRMEN1KMT2ALMNA | |
| SCHEMBL9075495 | 0.75 | MME (0.38) | SMN1; SMN2TSHRMEN1KMT2ALMNA | |
| SCHEMBL17676773 | 0.75 | MME (0.38) | SMN1; SMN2TSHRMEN1KMT2ALMNA | |
| SCHEMBL748887 | 0.75 | SMN1; SMN2 (0.53) | SMN1; SMN2TSHRLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |