SCHEMBL9075495

SCHEMBL9075495

CNC(=N)NC(C)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MME P08473 3/20 0.38
RAB9A P51151 1/20 0.38
ACE P12821 1/20 0.38
CPA1 P15085 1/20 0.38
ACE2 Q9BYF1 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.34
CA2 P00918 2/20 0.33
TP53 P04637 1/20 0.33
CA1 P00915 1/20 0.33
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.33
MEN1 O00255 1/20 0.33
TSHR P16473 1/20 0.33
KMT2A Q03164 1/20 0.33
LMNA P02545 1/20 0.33
FAAH O00519 1/20 0.33
LTA4H P09960 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17676773 1.00 MME (0.38) MMERAB9AACECPA1ACE2
Phosphoric Acid SCHEMBL9074634 0.92 LTA4H (0.36) MMERAB9AACECPA1ACE2
SCHEMBL16556784 0.75 SMN1; SMN2 (0.43) MMERAB9AACECPA1ACE2
SCHEMBL5126162 0.75 SMN1; SMN2 (0.43) MMERAB9AACECPA1ACE2
SCHEMBL29956892 0.75 SMN1; SMN2 (0.43) MMERAB9AACECPA1ACE2
SCHEMBL2797317 0.73
SCHEMBL21409564 0.73 ACE (0.39) MMERAB9AACECPA1ACE2
SCHEMBL15154265 0.73 MME (0.39) MMERAB9AACECPA1ACE2
SCHEMBL33799 0.73
SCHEMBL33800 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0426100-B1 Stabilized enzyme compositions ABBOTT LAB (US) 1994-12-14 EP claimed
EP-0426100-A1 Stabilized enzyme compositions ABBOTT LABORATORIES (US) 1991-05-08 EP claimed
US-20230248751-A1 NOVEL BIOENERGETIC/ANTI INFLAMMATORY THERAPY NOUR HEART, INC. 2023-08-10 US disclosed
US-5496716-A FOR USE AS CALIBRATOR OR CONTROL REFERENCE IN IMMUNOASSAY; CONTAINS ONE ENZYME SUBSTRATE OR ANALOG AND ENZYME PRODUCT OR ANALOG COMBINED WITH ENZYME ABBOTT LABORATORIES (US) 1996-03-05 US disclosed
EP-0426100-B1 Stabilized enzyme compositions ABBOTT LAB (US) 1994-12-14 EP disclosed