Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 11/20 | 0.64 |
| ▸ | NPC1 | O15118 | 5/20 | 0.62 |
| ▸ | RAB9A | P51151 | 5/20 | 0.62 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 3/20 | 0.60 |
| ▸ | MAOA | P21397 | 4/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15330790 | 1.00 | MAOB (0.64) | MAOBNPC1RAB9AHSP90AA1SMN1; SMN2 | |
| SCHEMBL2558347 | 0.83 | POLB (0.81) | MAOBNPC1RAB9AHSP90AA1SMN1; SMN2 | |
| SCHEMBL6815339 | 0.81 | POLB (0.77) | NPC1RAB9AHSP90AA1SMN1; SMN2POLB | |
| SCHEMBL3562732 | 0.81 | NPC1 (0.69) | NPC1RAB9AHSP90AA1SMN1; SMN2POLB | |
| SCHEMBL19984727 | 0.80 | NPC1 (0.67) | NPC1RAB9AHSP90AA1SMN1; SMN2POLB | |
| SCHEMBL29956346 | 0.79 | NPC1 (0.62) | MAOBNPC1RAB9AHSP90AA1SMN1; SMN2 | |
| SCHEMBL29954816 | 0.79 | MAOB (0.60) | MAOBMAOAKMT2A | |
| SCHEMBL2558882 | 0.79 | MAOB (0.60) | MAOBMAOAKMT2A | |
| SCHEMBL24141510 | 0.79 | NPC1 (0.61) | NPC1RAB9AHSP90AA1SMN1; SMN2POLB | |
| SCHEMBL68983 | 0.79 | MAOB (1.00) | MAOBMAOAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |