Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 13/20 | 0.60 |
| ▸ | MAOA | P21397 | 4/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.52 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.48 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29954816 | 1.00 | MAOB (0.60) | MAOBMAOANR4A2SRD5A2KMT2A | |
| SCHEMBL2559526 | 0.85 | MAOB (0.54) | MAOBMAOA | |
| SCHEMBL2560715 | 0.81 | MAOA (0.55) | MAOBMAOANR4A2SRD5A2KMT2A | |
| SCHEMBL15330790 | 0.79 | MAOB (0.64) | MAOBMAOAKMT2A | |
| SCHEMBL29956938 | 0.79 | MAOB (0.64) | MAOBMAOAKMT2A | |
| SCHEMBL68983 | 0.76 | MAOB (1.00) | MAOBMAOANR4A2SRD5A2KMT2A | |
| SCHEMBL2560777 | 0.75 | TP53 (0.60) | MAOBMAOANR4A2KMT2ANR4A1 | |
| SCHEMBL2559881 | 0.75 | ESR1 (0.63) | MAOBMAOANR4A2KMT2ANR4A1 | |
| SCHEMBL29953609 | 0.75 | ESR1 (0.63) | MAOBMAOANR4A2KMT2ANR4A1 | |
| SCHEMBL7505965 | 0.75 | NR4A2 (0.61) | NR4A2SRD5A2KMT2ANR4A1NR4A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11225655-B2 | Bi-functional complexes and methods for making and using such complexes | NUEVOLUTION A/S (DK) | 2022-01-18 | — | — | US | disclosed |
| EP-3540059-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2019-09-18 | — | — | EP | disclosed |
| EP-2558577-B1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION AS (DK) | 2018-12-12 | — | — | EP | disclosed |
| US-20130281324-A1 | BI-FUNCTINAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2013-10-24 | — | — | US | disclosed |
| EP-2558577-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | Nuevolution A/S (DK) | 2013-02-20 | — | — | EP | disclosed |
| WO-2011127933-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2011-10-20 | — | — | WO | disclosed |